Principium Psychiatry
115 E 57th St Suite 820 · New York, NY 10022
Midtown Manhattan psychiatry practice specializing in treatment-resistant depression. Spravato REMS-certified since 2019. Also offers IV ketamine and interventional psychiatry (TMS).
Treatments offered
Spravato (esketamine)
FDA-approved esketamine nasal spray. REMS-certified administration with 2-hour observation. Often insurance-covered for treatment-resistant depression.
Ketamine IV infusion
Intravenous infusion protocol. Continuous vital-sign monitoring, board-certified prescriber supervision.
Insurance and payment
Always verify coverage with the clinic and your plan before booking. Prior authorization is required for Spravato across all major payers.
Credentials on file
Each credential below is cross-checked against the issuing authority’s public lookup. Click any source to verify the license yourself.
Source: FDA_REMS. Re-verification runs on a rolling 30-day cycle. See our full methodology.
Sources & citations
Every factual claim on this page traces back to a public-record source. No self-reporting, no paid-inclusion data.
- Look up at FDA REMS
FDA REMS
License REMS-1021058
- Open state lookup
State medical board
New York State Department of Health - Office of Professions
- View NPI record
CMS NPI Registry
NPI 1336429081
- See on Google Maps
Patient reviews
4.9 avg across 214 Google reviews
Verification ingest
FDA_REMS - last checked 2026-04-09
Compare Principium Psychiatry against other New York options
See every verified provider in New York for each modality this clinic offers. Filter by insurance, price, and license body.
Similar providers in New York
Verified practices with at least one overlapping modality. Each is cross-checked against the same issuing authority.
Greenbrook TMS NeuroHealth - Buffalo
Buffalo, NY
Greenbrook operates 130+ Spravato REMS-certified treatment centers across the US. Buffalo location observes patients for the full 2-hour post-dose REMS monitoring window in private recovery suites.
Nushama
New York, NY
Madison Avenue ketamine clinic with a journey-based, therapeutic model. Six-session protocol includes preparation and integration therapy with licensed clinicians.
Salience Neuro Health - Austin
Austin, TX
Dual-modality Spravato and IV ketamine provider. Covered by most commercial plans for Spravato when treatment-resistant depression criteria are met. Board-certified anesthesiologist on staff.
Common questions
Where is Principium Psychiatry located?
Principium Psychiatry is at 115 E 57th St Suite 820, New York, NY 10022. Call +1 (212) 335-0236 or visit the clinic's site to confirm hours before your first visit.
What treatments does Principium Psychiatry offer?
Principium Psychiatry offers spravato (esketamine), ketamine iv infusion. Protocols, dosing, and observation requirements are set by the clinic and vary by modality - confirm the specifics during your intake call.
Does Principium Psychiatry accept insurance?
Principium Psychiatry accepts: Blue Cross Blue Shield, Aetna, Cigna, UnitedHealthcare, Optum. Coverage for a specific modality (Spravato, IV ketamine, etc.) depends on your plan tier, prior authorization, and documented medical necessity - verify with both your insurer and the clinic before booking.
How did LicensedPsychedelics verify this listing?
The license was cross-checked against FDA Spravato REMS registered. License numbers, expiration dates, and disciplinary status are rechecked on a rolling 30-day cycle. Last verification: 2026-04-09.
How much does a session at Principium Psychiatry cost?
Typical session pricing ranges from $575 to $1100. Actual cost depends on the specific modality, dose, and whether insurance is billed. Multi-session packages may be discounted - ask about induction pricing during your first call.