licensedpsychedelics

FDA REMS-verified - April 2026

Every verified Spravato clinic in Texas.

36 FDA REMS-certified sites across all five major Texas metros plus regional coverage in Amarillo, El Paso, Lubbock and Sherman. Every clinic on this page is cross-checked against the FDA Spravato REMS registry before publication. No affiliate relationships, no paid placement. Last verified 2026-04-20.

Before you call

Three things worth knowing first

Spravato is covered by insurance. Texas is a strong coverage state.

All 37 clinics can bill commercial insurance and Medicare. Texas Medicaid covers Spravato at most sites. Out-of-pocket after insurance is typically $10-$100 per session; cash pay is $6,000-$10,000 for induction.

You need a TRD diagnosis or acute suicidality.

Spravato is approved for treatment-resistant depression (failed 2+ antidepressants) or major depression with active suicidal ideation. Clinics will confirm your treatment history and psychiatric diagnosis at intake. It is not a first-line option.

Every session requires 2 hours of on-site monitoring.

Spravato is self-administered at the clinic and you must stay 2 hours for post-dose monitoring. No driving afterward. Induction is twice a week for 4 weeks; maintenance is once every 1-2 weeks. Plan logistics accordingly.

By metro

36 verified Spravato clinics across Texas

Austin4 sites

Four verified Spravato sites across central Austin. ANEW ERA combines Spravato with in-office IV ketamine under one roof; the other three are psychiatry-led clinics where Spravato is delivered in a monitored office bay.

Dallas-Fort Worth13 sites

DFW has one of the deepest Spravato networks in the South. Three verified sites in Dallas proper plus coverage north through Plano, Frisco, McKinney, Allen, Fairview and Denton - the whole Collin County ring is serviced.

Houston9 sites

Six verified Spravato sites inside Houston city limits plus adjacent coverage in Baytown, Katy and East Bernard. ANDALA MEDICAL TEXAS is the only Houston clinic offering all four FDA-regulated ketamine modalities (Spravato, IV, IM, oral) at a single location.

San Antonio5 sites

Four verified sites anchor San Antonio plus nearby New Braunfels. ANDALA MEDICAL TEXAS extends its four-modality footprint here as well, making San Antonio one of two Texas metros with full-stack ketamine access at a single clinic.

Rest of Texas5 sites

Regional coverage in Amarillo, El Paso, Lubbock and Sherman. These sites are often the only verified Spravato option within a 100-mile radius - meaningful in a state where the nearest REMS-certified clinic can otherwise be a 3-hour drive.

Insurance in Texas

Which Texas plans typically cover Spravato

  • Medicare (including Texas Advantage plans) covers Spravato as a Part B drug when delivered in a monitored office setting. Prior authorization usually required.
  • Texas Medicaid covers Spravato for patients with a documented TRD diagnosis. Not every clinic accepts Medicaid - ask directly before booking.
  • Blue Cross Blue Shield of Texas, Aetna, Cigna, United Healthcare, Humana- all cover Spravato as a specialty drug under mental health benefits. Expect $10-$100 copays.
  • Tricare (San Antonio has the largest Tricare base in Texas) covers Spravato for active duty, retired and dependents. Referral from a MTF provider often required.
  • VA benefits - several San Antonio VA clinics deliver Spravato directly. Veterans can also use the Community Care program to access any REMS-certified clinic on this list.

If you are outside a metro

Telehealth options for rural Texas

Spravato can only be delivered in-clinic. If you live more than 90 minutes from any of the 37 sites above, an at-home oral ketamine program may be a more practical starting point. These operate under telehealth prescribing rules and are covered in our at-home ketamine comparison.

Compare at-home ketamine

Texas Spravato: common questions

Is Spravato covered by insurance in Texas?

Yes. Spravato (esketamine) is the only FDA-approved psychedelic-adjacent therapy with broad private-insurance and Medicare coverage. All 37 clinics listed here can bill commercial insurance, Medicare, and most can bill Texas Medicaid for patients who qualify. Pre-authorization is typically required and is handled by the clinic. Out-of-pocket cost per session after coverage is usually $10 to $100 depending on plan.

How much does Spravato cost without insurance in Texas?

List price for the drug itself runs around $600 to $900 per treatment session, paid directly to the specialty pharmacy. The clinic separately bills for the required 2-hour monitoring visit, typically $150 to $300. A full induction course (8 sessions over 4 weeks) generally totals $6,000 to $10,000 in cash pricing, followed by maintenance dosing every 1-2 weeks. Most patients only pursue Spravato through insurance because the economics without coverage are prohibitive.

What's the difference between Spravato and IV ketamine?

Spravato is FDA-approved, standardized in dose, covered by insurance, and delivered via nasal spray under REMS monitoring. IV ketamine is off-label, dosed by body weight, paid out of pocket in most cases, and delivered via infusion over 40 minutes. Spravato is the insurance-friendly path; IV ketamine is generally considered more potent but costs $400 to $800 per session out of pocket. Several clinics on this list offer both.

How are these clinics verified?

Every clinic listed here is cross-checked against the FDA Spravato REMS registry before publication. Spravato can only be administered at REMS-certified sites - the FDA maintains a public list of every certified clinic in the country. We re-verify on a rolling 90-day cycle. If a clinic's REMS certification lapses, surrenders, or is subject to action, it is removed within 7 days. NPI numbers and state medical licenses are cross-referenced separately.

Do I need a referral for Spravato in Texas?

No. Texas does not require a physician referral to start a Spravato evaluation. You can self-refer directly to any REMS-certified clinic on this list. The clinic will conduct its own psychiatric intake and confirm Spravato is appropriate for you. Most clinics on this list handle the prior authorization paperwork for insurance internally.

What conditions is Spravato approved to treat?

Spravato is FDA-approved for two conditions: treatment-resistant depression (TRD) in adults who have failed 2 or more antidepressants, and major depressive disorder with acute suicidal ideation or behavior. It is not first-line treatment for depression - clinics will confirm your treatment history before starting. Some clinics on this list also offer off-label ketamine IV for anxiety, PTSD, OCD and chronic pain.

Which Texas metros have the most Spravato coverage?

DFW has the deepest network with 13 verified sites across Dallas, Plano, Frisco, McKinney, Allen, Fairview, Bedford and Denton. Houston has 9 sites including Baytown, Katy and East Bernard. San Antonio has 5 including New Braunfels. Austin has 4. Rural and regional Texas has 4 (Amarillo, El Paso, Lubbock, Sherman). If you are outside these metros, the closest clinic may be a 2-3 hour drive and a telehealth-only program like Mindbloom or Wondermed may be a better fit.

LicensedPsychedelics is an independent, license-verified directory. We receive no payment from any clinic on this page. Spravato is an FDA-approved prescription therapy; this page is not medical advice. Call 988 in a mental health crisis or your provider for an urgent consultation. Always confirm licensure directly with the clinic before starting treatment.