Metro hub
Psychedelic therapy providers in Portland, OR
Licensed Oregon Psilocybin Services (OPS) service centers operate under the Oregon Health Authority. Also a strong ketamine + Spravato market.
Every clinic on this page has a current license verified against the FDA REMS registry, Oregon medical board, or the state-specific regulator covering the modality. We do not accept payment for placement.
- Verified in metro
- 5
- State-wide
- 9
- Modalities available
- 4
- Regulator
- Oregon medical board + FDA
Psilocybin (Oregon licensed) in Portland
4 verified providers
Alma Institute
Portland, OR
Portland service center tied to one of Oregon's largest licensed facilitator training programs. Trainees shadow sessions with client consent.
Fractal Soul
Portland, OR
Couples and dyad sessions alongside standard 1:1 programming. Known for LGBTQ+ affirming facilitation and a sliding-scale equity fund.
Helena Healing
Portland, OR
NE Portland service center in a converted Craftsman-era home. Offers a reduced-fee spot each cohort for clients on SNAP, WIC, or Medicaid.
Third Wave Therapeutics
Portland, OR
Downtown Portland service center with a clinical-plus-concierge model. Private 400-square-foot session rooms, professional musician-curated playlists, and extended overnight integration option.
Spravato (esketamine) in Portland
1 verified provider
Ketamine IV infusion in Portland
1 verified provider
Ketamine IM injection in Portland
1 verified provider
Before you book in Portland
Confirm the license body before you pay
Every clinic should be able to give you a license number and the issuing body (FDA REMS ID, state medical board number, OHA/DORA license). You can look it up on the regulator's public registry before your first session.
Ask who is in the room during dosing
A prescriber does not need to be present for every moment of an IV or Spravato session, but a qualified clinician must be. Ask for specifics: RN, nurse practitioner, or MD, and what happens if you have an adverse reaction.
Get the pre-authorization status in writing
For Spravato, your insurer should issue a prior-auth confirmation with a validity window and session count. Do not start induction without a copy in hand - retroactive denials are common.
Clarify cancellation and missed-session policies
Induction courses are typically 6-8 sessions. If you cancel or miss, many clinics will not refund the deposit but should let you reschedule within a reasonable window. Get this in writing.